This code is an example for calculating time difference in different units. It is a part of my one program.
import pandas as pd
DateOct02_2020=date(2020,10,2)
# ...
data=pd.read_csv(file)
data['Date']=pd.to_datetime(data.Date)
L=data.shape[0]
for i in range(L):
date1=data.loc[i,'Date'].date()
ddt=DateOct02_2020-date1
print(int(ddt.total_seconds())) # in seconds
print(int(ddt.total_seconds()/60)) # in minutes
print(int(ddt.total_seconds()/60/60)) # in hours
print(int(ddt.total_seconds()/60/60/24)) # in days